IVF, simple to say and complicated to say

To put it simply, as we talked about in our previous article, “Why IVF Success Rates are High in the US”: the current live birth rate for transplants in the US is already very high at 70%, which suggests that with PGT-A-passing first-degree blastocysts, you’re actually pretty close to success.

It’s complicated because it’s not easy to get a first-degree blastocyst that passes PGT-A. So, how do you get a first-degree blastocyst that passes PGT-A?

1、Choose the right doctor to take out more high-quality eggs after an ovulation treatment cycle

2. Give the eggs to an embryologist to grow more blastocysts.

I. How to choose the right doctor?

The most important thing is a medical checkup: the purpose of a medical checkup is to know your body.A lot of women say to us, “I thought I’d pick a doctor and then do a physical,” but of course not!

As an example: a 45-year-old mother-to-be felt that her body was great and she had no problem at all with her second child, only to find out that she had an AMH of 0.06 and one basal follicle after finding her doctor for a physical examination, and as a result, both public and private hospitals in mainland China felt that there was no hope for her and were unwilling to accept her.

Another example: a young mother-to-be, 29 years old, listened to the so-called sister’s experience and chose a “highly skilled” doctor, the result is not a difficult family according to the difficult family program of ovulation treatment, the result is that obviously can be obtained 10 P through the blastocysts, but in the end only got 4.

Blah blah blah …… There are countless examples like this.

Physical exams can help us

Recognize your fertility and target a range of doctors and clinics.

With the medical report, the doctor has the basis to help us assess: how many eggs can be retrieved, how many blastocysts can be raised, and how many embryos can be transferred in a single cycle of ovulation. As well as the results of the evaluation, whether it meets the expectations of the parents-to-be, whether it is possible to start the cycle immediately.

Some prospective parents go to Japan or the United States without a medical checkup to start ovulation promotion, only to be checked for inflammation, or syphilis just after paying the money, and have to cancel the cycle. As a result, they have to: they have spent money, they are tired, and they can’t do anything.

With the medical report to find us, generally we will target the clinic and doctor range according to the guest’s ovarian fertility and physical condition, and based on the results of thousands of treatment cases to find guests with similar fertility, matching the most suitable doctors and clinics, to help the guest to get the maximum success rate.

Of course, parents-to-be can also choose their own clinic and doctor, and here’s a few things to consider to help you out as well

1, the data of egg retrieval is not the more the better, the number of eggs retrieved is not equal to the success rate.

We have seen too many cases of taking 37, 8, and eventually only 4 or 5 sacs, and take 20 or so dozen, can also be 4 or 5 sacs, do not think that the more eggs to get the better, to promote out of the high quality of eggs, in order to run to the end of the day, only to be counted as a win.

2. Choosing the right ovulation program will help improve egg quality and early success.

Many people say that egg quality isn’t related to the mother-to-be’s body? Yes, it is true that the woman’s body plays the vast majority of the factors, but since it is the treatment, it is important to choose the right ovulation program to improve the quality of the eggs .

At the same time, we analyzed the results of thousands of patients by comparing their ovulation results and learned that

1) 60 %～70% doctors specialize in only one type of ovulation regimen, most typically the long regimen. Only suitable women choose the long protocol to achieve good results

(2) Most of the “personalization” is just an increase in the time allocated for patient interviews and a slight change in the dosage of medication based on the original regimen, and so on, and the results will not be much improved.

(3) Some deans will lead their doctors to delve into a long-term program that is different from the long program, such as antagonistic prophylaxis, or luteal prophylaxis, or microprophylaxis, or modified microprophylaxis, or enhanced microprophylaxis, etc., which gives hope to the patients who are insensitive to the body’s response to a certain type of drug or who have difficulty in conceiving.

(4) Some doctors are bold and careful, willing to take the trouble to study 2 to 3 types of ovulation programs, and the ovulation program is also flexible and will be adjusted according to the customer’s physical response to the program.

3. Don’t be overly obsessed with treatment options, everything is about having high quality blastocysts first.

Treatment options mainly refer to, IVF, egg freezing, Mai sperm, Mai egg, Dai pregnancy, transplantation to choose a single or twin fetus, and so on. We have seen a lot of older women, come up and ask the clinic Dai pregnancy is friendly, Dai pregnancy is not friendly clinic is passed away, we often feel sorry. Often, younger women can choose a clinic based on whether it is surrogacy friendly or not, and we encourage this choice; however, it is not recommended for older or fertility-challenged patients (we may be resisted by many of our peers if we say this, but we really don’t want to see more older women end up with ‘Mai eggs’ due to a wrong choice and a blow to their confidence), and some of them end up with ‘Mai eggs’. Some clinics with high live birth rates for older patients are not very friendly to Dai pregnancies, but they can help us make high-quality embryos, which doctor can help us make more high-quality blastocysts, and we will promote ovulation with whoever we want. Once we have the blastocysts, we can then choose to carry the embryos ourselves, transfer them to other clinics for Dai pregnancy, or wait for 1 to 2 years before we have a chance to find a Dai mother.

Note, Dai pregnancy unfriendly mainly refers to: 1, clinics need more reasonable “Dai pregnancy reasons”, usually endometrial thickness, scarring and other minor problems are not allowed to generation; 2, clinic process is friendly, such as clinics let the prospective parents to do three times the chromosome test, or let the surrogate mother medical examination on the run three times, or must do “simulated transplant”, or height can not be lower than xx, etc., anyway, there are a lot of various normal or abnormal reasons.3, whether there are a lot of Dai pregnancy companies do not cooperate with them because the clinic on the surrogate mother’s medical records review time is too long, the degree of cooperation is not high ….. etc.) 4, because Dai pregnancy extra increase expenses etc.

Second, how to choose a reliable embryologist?

As we mentioned earlier, after a woman’s ovulation retrieval, the eggs have to go through layers of screening such as egg maturation, fertilization, raising into day 3 embryos, day 5-7 blastocysts, and then sending them for PGT testing, and most of this work is done in the IVF laboratory (only the PGT testing is done in the genetics laboratory.) The environment, technology, equipment, and especially the expertise of the embryologist in IVF are the key factors in the cultivation of high-quality blastocysts. Although we are incredibly attached to the outcome of each step, in fact, what happens after the egg retrieval is no longer relevant to us, and I say no, because all of this work is done for us in the lab by the embryologist, and we can’t influence or participate in it, however! We have a choice, we can choose a reliable lab (aka clinic) before doing IVF.

How to choose a reliable lab?

1. The most intuitive result is to look at the data, or to see if the results of recent patients’ sacs have been stable. Embryologists in the United States are usually categorized as junior embryologists, senior embryologists, and IVF lab directors who work to ensure that the lab is an ideal environment for embryo growth and storage. Embryologist turnover, poor management systems, or insufficiently high grades can affect the results of sac raising.

2, clear whether they have special needs: some patients eggs need laser-assisted incubation, IVM immature egg culture, screening sperm x or sperm y and egg x combination (xx girl, xy boy), and because of the sperm’s vitality, poor morphology, etc. need to resort to the laboratory of other technical needs, etc., you can and the doctor for the first time to ask whether the laboratory to provide the relevant technology, of course, most people do not have these Of course, most people do not have these needs.

3. Look at the qualifications of the embryologist.

…… Wait, wait, wait, wait.

Apart from the above, what are the other things that we must know?

1. The United States is a system of separation of medicine.

Most clinics in Southern California will have IVF packages that include fertility drugs, but not many of them do, and most US clinics do not sell fertility drugs. Therefore, after each visit to the clinic for blood draws, ultrasound, and doctor’s appointment, clients need to go to the pharmacy to buy medication based on the doctor’s instructions. Before buying drugs, remember to tell the doctor that you want to specify the pharmacy, generally choose a pharmacy close to your home, or closer to the clinic is better, and home from the clinic, for example, it is best not to be too far away from the clinic, to avoid questions about the medical advice need to return to the clinic to ask, the road is too far away, too long a time to come back and forth to delay things.

2. Clinic management and services

Ovulation therapy is unfamiliar to most parents-to-be. In mainland China, you have to get up early every day to get blood drawn and ultrasound, then wait for the blood test report, line up to see the doctor with the blood test report, and then get medication and injection after the doctor has given you the medical advice. ….. Just like this, half a day passed, sometimes the whole day just like this, the whole person is very anxious. But the good thing about continental ovulation is: every time you go to the clinic, you can see the doctor.

Some clinics in the U.S. are the same as the mainland, you can see the doctor every time, the doctor personally do ultrasound, give medical advice in person, the whole time in the clinic is about 1 hour, easy like traveling; however, there are many clinics only the first time you can see the doctor at the initial consultation, most of the other is through the doctor’s assistant to communicate, or through the doctor’s assistant to convey the medical advice. So, while choosing a doctor

1) It is also vital to examine and evaluate the physician’s assistant, and being able to answer questions at any time, or communicate smoothly when in doubt, is also a big concern for many prospective parents.

2) Clinic finances. U.S. bills are usually notified by mail or postal mail, and the lead time for bills to come out is long, and the address to receive the bill, and the reasonableness of the fees charged are also critical.

3. Ovulation-promoting treatment, the woman’s mindset is crucial

Keep enough sleep, happy mood, reasonable diet, etc., helps to secrete benign hormones, which is very helpful to improve the quality of eggs Oh.

In closing, I wish all prospective parents the best of luck in finding the right doctor for a successful outcome.